Nucleus decides the future cell division site?
We are at the very beginning of our understanding that nucleus decides the future cell division site. The pivotal role in nuclear movement is played by nuclear envelope proteins. We are trying to systematically dissect which nuclear envelope proteins are involved in nuclear movement prior to asymmetric cell division. To answer this questions, we are using subsidiary cell during stomatal development in maize and lateral root development in the Arabidopsis. In both cases, the nucleus requires to move prior to asymmetric cell division. We combine our expertise on plant physiology, genetics, molecular, and cell biology to tackle this question.
We are at the very beginning of our understanding that nucleus decides the future cell division site. The pivotal role in nuclear movement is played by nuclear envelope proteins. We are trying to systematically dissect which nuclear envelope proteins are involved in nuclear movement prior to asymmetric cell division. To answer this questions, we are using subsidiary cell during stomatal development in maize and lateral root development in the Arabidopsis. In both cases, the nucleus requires to move prior to asymmetric cell division. We combine our expertise on plant physiology, genetics, molecular, and cell biology to tackle this question.
Nuclear membrane proteins regulate the cell division?
Nucleus maintains intact double layer membranes. During the cell division, nuclear envelope breakdowns and at the end of the mitosis, the envelope reappears in the daughter cell nucleus. In the meantime, the nuclear envelope proteins are observed to co-localize with mitotic apparatus. We are interested to know the function of nuclear envelope proteins during the mitosis. To answer this questions, we use symmetric cell division using the leaf meristematic region of maize and root meristematic region of Arabidopsis. This project harness the power of genetic and cell biology tools to perform the experiments.
Nucleus maintains intact double layer membranes. During the cell division, nuclear envelope breakdowns and at the end of the mitosis, the envelope reappears in the daughter cell nucleus. In the meantime, the nuclear envelope proteins are observed to co-localize with mitotic apparatus. We are interested to know the function of nuclear envelope proteins during the mitosis. To answer this questions, we use symmetric cell division using the leaf meristematic region of maize and root meristematic region of Arabidopsis. This project harness the power of genetic and cell biology tools to perform the experiments.
Nuclear membrane proteins respond to environmental stress?
During the stress condition, cell cortex perceives signals and relay the signal through cytoskeleton to the nuclear envelope; and nuclear envelope relays that signal towards the inner part of the nucleus and regulates the gene expression. This classic model connects the environmental stress and cellular organelle. In this process, nuclear membrane plays a pivotal role. Nuclear envelope regulates this response either by relaying signal from cytoplasm to nucleus or by controlling exchange of biomolecules between cytoplasm and nucleus. In this project, we are more focused on studying the plant physiology, molecular biology, and cell biology aspects during an array of environmental stresses.
During the stress condition, cell cortex perceives signals and relay the signal through cytoskeleton to the nuclear envelope; and nuclear envelope relays that signal towards the inner part of the nucleus and regulates the gene expression. This classic model connects the environmental stress and cellular organelle. In this process, nuclear membrane plays a pivotal role. Nuclear envelope regulates this response either by relaying signal from cytoplasm to nucleus or by controlling exchange of biomolecules between cytoplasm and nucleus. In this project, we are more focused on studying the plant physiology, molecular biology, and cell biology aspects during an array of environmental stresses.
